MLF: Affinity biosensors for COVID-19 antibodies

Affinity biosensors rely on high affinity bioreceptor: analyte interaction between, e.g an antibody and biomarker protein. Signal transduction by electrochemical impedance gives highly sensitive detection, in this case of COV-SARS-2 spike protein by its cognate antibody. The system also works “in reverse”; the recombinant spike protein can be used as receptor and such sensors are highly sensitive, detecting just a few 100s of viral particles in a sample.